Summary
Differentials
Common
- Thoracic aortic aneurysm
- Non-Hodgkin's lymphoma
- Metastatic cancer
- Thymoma
- Lung cancer
Uncommon
- Aortic dissection
- Hodgkin's lymphoma
- Mediastinal germ cell tumour: seminoma
- Mediastinal germ cell tumour: non-seminoma
- Thymic carcinoma
- Primary tracheal tumours
- Neurogenic tumour
- Thyroid neoplasm
- Substernal goitre
- Acute lymphocytic leukaemia
- Chronic lymphocytic leukaemia
- Pericardial cyst
- Bronchogenic cyst
- Oesophageal cyst (includes oesophageal duplication cyst)
- Mediastinal germ cell tumour: mature teratoma
Contributors
Authors
Ashok Muniappan, MD
Assistant Professor of Surgery
Division of Thoracic Surgery
Massachusetts General Hospital
Harvard Medical School
Boston
MA
Disclosures
AM declares that he has no competing interests.
Acknowledgements
Dr Ashok Muniappan would like to gratefully acknowledge Dr John Kucharczuk, Dr Mario Gasparri, and Dr Nicholas Choong, the previous contributors to this topic. JK, MG, and NC declare that they have no competing interests.
Peer reviewers
Marc Baker, MD, PhD
Cardiology Fellow
Department of Internal Medicine
Cardiology Division
University of Rochester
Rochester
NY
Disclosures
MB declares that he has no competing interests.
Abe DeAnda Jr., MD, FACS, FAHA
University Associate Professor
Cardiothoracic Surgery
Albert Einstein College of Medicine
Director Aortic Surgery
Montefiore Medical Center
Bronx
NY
Disclosures
AD declares that he has no competing interests.
Shahab A. Akhter, MD
Assistant Professor of Surgery
Section of Cardiac and Thoracic Surgery
The University of Chicago
Chicago
IL
Disclosures
SAA declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Duwe BV, Sterman DH, Musani AI. Tumors of the mediastinum. Chest. 2005;128:2893-2909.Full text Abstract
Silvestri GA, Gonzalez AV, Jantz MA, et al. Methods for staging non-small cell lung cancer: diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013;143(5 Suppl):e211S-e250S.Full text Abstract
Annema JT, van Meerbeeck JP, Rintoul RC, et al. Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial. JAMA. 2010;304:2245-2252.Full text Abstract
Marom EM, Milito MA, Moran CA, et al. Computed tomography findings predicting invasiveness of thymoma. J Thorac Oncol. 2011;6:1274-1281. Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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